How much is fluticasone propionate (Flonase) without insurance?

The generic version of Flonase, fluticasone propionate, costs $70 without insurance. Learn how to get fluticasone propionate at a lower price, or find cheaper alternatives.

Is fluticasone propionate covered by insurance? | How much does fluticasone propionate cost without insurance? | How to get fluticasone propionate without insurance

Fluticasone propionate is a generic corticosteroid nasal spray. Over-the-counter (OTC) fluticasone nasal spray relieves the symptoms of seasonal allergies and hay fever symptoms including runny nose, nasal congestion, sneezing, itchy nose, and watery eyes. A small bottle of over-the-counter fluticasone propionate nasal spray will cost less than $20. There is also a higher-priced prescription fluticasone nasal spray with a dosage strength twice that of the OTC fluticasone nasal spray. Healthcare professionals use it to treat nasal polyps due to nasal and sinus swelling. Still, the FDA has not approved it to treat allergy symptoms. 

What is the brand name for fluticasone propionate?

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Most people know fluticasone propionate nasal spray by the brand-name Flonase Allergy Relief. Flonase Allergy Relief costs about $7 for a 16-gram spray bottle. Remember that other Flonase products, such as Flonase Sensimist (fluticasone furoate) and Flonase Nighttime Allergy Relief (triprolidine), do not contain fluticasone propionate. Prescription fluticasone nasal spray is only available under the brand name Xhance.

Don’t be confused with other fluticasone propionate products when picking up a prescription for fluticasone propionate. Fluticasone propionate HFA and its brand name, Flovent, are asthma maintenance treatment inhalers. Inhalers are administered by breathing in a puff of medication through the mouth. Fluticasone propionate cream, gel, or lotion are all applied to the skin. Healthcare providers may refer to these topical medicines under the brand name Cutivate.

Is fluticasone propionate covered by insurance?

Health insurance plans usually cover fluticasone propionate nasal spray, as do Medicare Part D plans, and Medicaid, but coverage may vary. Some insurance companies, such as Kaiser Permanente do not cover over-the-counter drugs. Most insurance companies have fluticasone propionate nasal spray in their lowest copay tier. Still, the final out-of-pocket cost will be affected by any deductibles, coinsurance, or coverage gap policies will affect the final out-of-pocket cost.

Prescription Xhance may or may not be covered by health insurance. When it is, the insurance company usually places it in the higher copay tiers.

How much does fluticasone propionate cost without insurance?

Without insurance, a 16 gm, 50 mcg/actuation nasal spray bottle of over-the-counter Flonase Allergy Relief costs about $19. This is enough medicine for 120 sprays. The recommended dose is two sprays in each nostril once daily, so a 16 gm bottle has enough medication for 30 days of daily use at 60 cents per day.

Prescription fluticasone nasal spray is another matter. Available only under the brand-name Xhance, a 30-day supply costs about $770.

Generic fluticasone propionate is the lowest-cost steroid OTC nasal spray. Nasonex 24HR Allergy (mometasone furoate) and Rhinocort Allergy Spray (budesonide) cost about the same as or slightly more than Flonase. Uninsured people with an Xhance prescription can ask the prescribing healthcare provider about substituting prescription mometasone furoate nasal spray to save money.

For allergy symptoms, oral antihistamines are an effective and lower-cost allergy relief substitute. They include generic Benadryl (diphenhydramine), Claritin (loratadine) , Zyrtec (cetirizine), and Allegra Allergy (fexofenadine). However, some antihistamines have many troublesome side effects, such as drowsiness, dizziness, and potentially rare but severe allergic reactions. On the other hand, oral antihistamines don’t cause nasal irritation, nosebleeds, and nose sores like steroid nasal sprays can do. Before making the switch, get medical advice from a healthcare professional.

The least expensive option would be to use a SingleCare prescription discount card when buying generic or brand-name fluticasone nasal spray. The lowest SingleCare price for over-the-counter fluticasone propionate nasal spray is only $7. 

Compare Flonase (fluticasone propionate) prices to related drugs

Fluticasone propionate$70 per 1, 16 gm of 50 mcg/act suspension$7 per 1, 16 gm of 50 mcg/act suspension of generic fluticasone propionateSee latest prices
Brand-name fluticasone propionate 


$19 per 1, 9.9 mL 50 mcg/act bottle$3 per 1, 9.9 mL 50 mcg/act bottle of brand-name FlonaseSee latest prices
Mometasone furoate$257 per 1, 17 gm of 50 mcg/act suspension$32 per 1, 17 gm of 50 mcg/act suspension of generic mometasone FuroateSee latest prices


$265 per 1, 23 gm of 137-50 mcg/act suspension$57 per 1, 23 gm of 137-50 mcg/act suspension of brand-name DymistaSee latest prices
Fexofenadine$38 per 1 bottle of 100, 90 mg tablets $6 per 1 bottle of 100, 90 mg tablets of generic fexofenadineSee latest prices
Diphenhydramine$65 for 25, 1 mL of 50 mg/mL vials$6 for 25, 1 mL of 50 mg/mL vials of generic diphenhydramineSee latest prices

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the link under “Savings options” to see the latest drug prices.

How to get fluticasone propionate without insurance

With or without insurance, people often pay the full cash price for over-the-counter allergy medications like Flonase or its generic version. The retail price is not the final word, however. A SingleCare savings card is often the best place to start when looking for discounts or savings on prescription or over-the-counter medications. 

1. Use a SingleCare discount card

With a free coupon from SingleCare, a 30-day supply of fluticasone propionate nasal spray can cost as little as $7. SingleCare participating pharmacies offer different discount prices, so go to SingleCare’s fluticasone propionate coupons page to shop discount prices. Read the FAQs to find more savings and drug information about fluticasone nasal spray.

2. Find the lowest price 

Shopping for the best price goes much faster when people start with SingleCare’s pricing history for fluticasone propionate nasal spray. There, you’ll find that the lowest pharmacy price for fluticasone nasal spray is $40 less than the highest pharmacy price, saving more than $400 annually. Locate the best price on this table and then locate the nearest local pharmacy on SingleCare’s pharmacy finder.

3. Switch to antihistamines

Antihistamines, such as diphenhydramine and chlorpheniramine, are reasonable alternatives to steroid nasal sprays. However, they may have an unwanted side effect of drowsiness. Loratadine is the cheapest non-drowsy antihistamine, but is more expensive than fluticasone propionate spray. Drowsiness is a problem, but consider that long-term use of fluticasone nasal spray can cause rare but serious side effect of glaucoma or cataracts. 

4. Get medical advice about alternatives to prescription fluticasone spray

If prescribed Xhance for nasal polyps, talk to the prescriber about alternative treatments. Generic prescription mometasone furoate is a lower-priced alternative. Ask also about substituting over-the-counter fluticasone spray. The dosage strength is lower, so there may be issues with making the switch. A healthcare professional can help make the decision.


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